Enterovirus-71 (EV-71) is a common etiologic agent of hand-foot and mouth (HFMD) disease which is mainly a disease of
children <10 yrs. Although prodrome symptoms of HFMD are self resolving, the EV-71 can also cause severe neurologic disease
including encephalitis, meningitis, and polio-like paralysis. In particular, EV-71 has caused epidemics in the Western pacific
region such as Taiwan (1998), Singapore (2000) and China (2007)
This DiseaseINFOPACK provides an up-to-date comprehensive review of current literature pertaining to Enterovirus-71 virus including
its epidemiology (outbreaks), surveillance and dynamics. Because of its potential to cause mortality and severe morbidity in children, and regional significance, EV-71 appears a plausible
target for a vaccine-based preventative approach. EV-71 is under consideration by a number of commercial manufacturers.
