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MarketVIEW: Ebola virus vaccines

Published: April 2015

Ebola virus is a member of the Filoviridae family, which can cause a zoonotic disease in humans. The virus can be transmitted between humans via contact with infected body fluids or large droplets of infected fluids, causing a sudden disease with flu-like symptoms, digestive disorders and hemorrhaging. The mean case fatality of historical outbreaks is around 65%. Most Ebola outbreaks occur in central Africa, although latest outbreak is focused on West Africa with around 25,000 cases and over 10,000 deaths (March 2015). It is estimated that the West African region will lose between $3.6 and $4.9 billion in GDP per year for the next 3 years (UNDP figures).

A number of manufacturers are investigating Ebola vaccines in clinical studies. Major companies involved include Okairos/NIAID (GSK), Newlink/PHAC/Merck & Co, Johnson & Johnson. The most advanced in cAd3-EBOZ in Phase II/III Okairos/NIAID (GSK). A number of small molecules, gene silencing technologies and monoclonal antibodies are also being investigated.

This MarketVIEW product contains a comprehensive MS Excel-based model + summary presentation that forecasts the potential commercial value of Ebola vaccines across relevant African countries until 2030. The model contains value ($ m) and volume (mio doses) predictions per vaccine type /per LO/BASE/HIGH scenarios along with timeframe, pricing and penetration estimates for all target populations/stockpile maintenance. The product also includes an in depth review of latest Ebola epidemiological trends, treatments/guidelines and latest developments in R&D.


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