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MarketVIEW: universal pneumo vaccines

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Vaccines to prevent serious infections caused by Streptococcus pneumoniae or "pneumo" currently form the largest component of the global vaccine market ($4 - 5bn/yr). Notable examples are Prevnar/Prevenar (PCV7) first marketed to cover the seven most common US serotypes causing infant invasive pneumococcal disease (IPD) and now recently extended to a new 13-valent form (PCV13). Pfizer vaccines (formerly Wyeth) are also expanding PCV13 indications into older age groups especially those with underlying co-morbidities who are currently vaccinated with 23-valent Pneumovax (PPSV). Pneumococcal vaccines are being rolled out to GAVI-funded markets in developing countries where the burden of pneumo related diseases is more extreme.

The ultimate Pneumo vaccine would be able to prevent disease covered by the majority of ~90 serotypes, cheap to produce and therefore available on a global scale. Investigators in both the commercial and academic/not-for-profit sector are investigating these "universal" protein-based vaccines (PUPV) which could eventually replace conjugated forms although many development challenges remain.

This MarketVIEW product is a comprehensive opportunity assessment focused on understanding the commercial potential of new "universal" protein-based vaccines should they be licensed. As well as an Executive presentation, the product contains two detailed value/volume forecast models at the country level which detail all the latest dynamics between product forms and all target groups being in mind evolution in US/EU/ROW policy recommendations. The possible entry of new PUPV(s) is then modelled and current development issues/approaches discussed.


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